Welcome to the website of the European project SYSCILIA, “A systems biology approach to dissect cilia function and its disruption in human genetic disease”. SYSCILIA is a large scale integrating project funded by the European Community's Seventh Framework Programme (FP7/2007-2013) under the Health Cooperation Programme. The duration of the project is 60 months, starting from June 1st 2010. It brings together 18 partners from seven different countries.
The aim of SYSCILIA is to identify the molecular mechanisms characterizing cilium function, and the discrete perturbations associated with dysfunction caused by mutations in inherited ciliopathies, applying a systems biology approach. Our overall objectives are to establish a paradigm for studying and modelling complex eukaryotic systems, to understand how system perturbation contributes to the modulation of clinical phenotypes, and to provide a better understanding of ciliary processes in biology and their associated diseases.